Adrenocorticotropic Hormone (ACTH)

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Adrenocorticotropic hormone (ACTH) peptide is also known as corticotropin, it is secreted by the anterior pituitary gland. This peptide hormone has 39 amino acids, it is a cleavage product from the precursor of proopiomelanocortin (POMC). ACTH is the important component of hypothalamic-pituitary-adrenal axis, as a response to biological stress. Its secretion is triggered by the corticotropin-releasing hormone (CRH) from hypothalamus. Then it stimulates the secretion of steroid hormone through the cell membrane receptor (ACTH-R), such as glucocoticoids in the adrenal cortex.

ACTH(1-39) is the full-length ACTH, ACTH(1-24) is conserved across species with 75% potent as ACTH，ACTH(1-10) alter blood pressure with no ACTH activity, ACTH(4-10) has neurological effects.

Notice: All peptides are only for research purposes, Not for clinical use.

ACTH Peptides

  • Name: ACTH (1-39), human
  • Sequence: SYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEF
  • CAS Number: [12279-41-3]
  • Formula: C207H308N56O58S1
  • Characteristics: None
  • Reference: D. Yamashiro et al, JACS, 95, 1310 (1973)  N.Y. Ann. Acad. Sci., 297,1-641 (1977)
  • Name: ACTH (18-39), human
  • Sequence: RPVKVYPNGAEDESAEAFPLEF
  • CAS Number: [53917-42-3]
  • Formula: C112H165N27O36
  • Characteristics: None
  • Reference: L.I. Larsson, Histochem., 55, 225 (1978)
  • Name: ACTH (1-24), human
  • Sequence: SYSMEHFRWGKPVGKKRRPVKVYP
  • CAS Number: [16960-16-0]
  • Formula: C136H210N40O31S1
  • Characteristics: None
  • Reference: Y.F.Jacquet, Science, 201, 1032 (1978)
3.ACTH (1-24), human
  • Name: ACTH (1-13), human
  • Sequence: SYSMEHFRWGKPV
  • CAS Number: [22006-64-0]
  • Formula: C75H106N20O19S1
  • Characteristics: None
  • Reference: None
5.ACTH (1-10), human
  • Name: ACTH (1-10), human
  • Sequence: SYSMEHFRWG
  • CAS Number: [2791-05-1]
  • Formula: C59H78N16O16S1
  • Characteristics: None
  • Reference: None
6.ACTH (4-10), human
  • Name: ACTH (4-10), human
  • Sequence: MEHFRWG
  • CAS Number: [4037-01-8]
  • Formula: C44H59N13O10S1
  • Characteristics: None
  • Reference: R. Schwyzer et al., FEBS Letters, 19, 229 (1971)
7.ACTH (4-11), human
  • Name: ACTH (4-11), human
  • Sequence: MEHFRWGK
  • CAS Number: [67224-41-3]
  • Formula: C50H71N15O11S1
  • Characteristics: None
  • Reference: R. Schwyzer et al., FEBS Letters, 19, 229 (1971)
8.ACTH (1-39), mouse, rat
  • Name: ACTH (1-39), mouse, rat
  • Sequence: SYSMEHFRWGKPVGKKRRPVKVYPNVAENESAEAFPLEFz
  • CAS Number: [77465-10-2]
  • Formula: C210H315N57O57S1
  • Characteristics: None
  • Reference: Drouin, Nature, 288, 610 (1980)  E. Oates and E. Herbert, J. Biol. Chem., 259, 7421 (1984)  J. Drouin et al., FEBS Letters, 193, 54 (1985)
9.[D-Lys16]-ACTH (1-24)
  • Name: [D-Lys16]-ACTH (1-24)
  • Sequence: SYSMEHFRWGKPVGKkRRPVKVYP (Remark:k is D-Lys)
  • CAS Number: [494750-52-6]
  • Formula: C136H210N40O31S
  • Characteristics: None
  • Reference: None
10.[D-Ser1]-ACTH (1-24), human
  • Name: [D-Ser1]-ACTH (1-24), human
  • Sequence: sYSMEHFRWGKPVGKKRRPVKVYP (Remark:s is D-Ser)
  • CAS Number: [26469-81-8]
  • Formula: C136H210N40O31S
  • Characteristics: None
  • Reference: None
11.[Glu10]-ACTH (1-17)
  • Name: [Glu10]-ACTH (1-17)
  • Sequence: SYSMEHFRWEKPVGKKR
  • CAS Number: None
  • Formula: C98H149N29O25S
  • Characteristics: None
  • Reference: None
12.[Phe2, Nle4]-ACTH (1-24)
  • Name: [Phe2, Nle4]-ACTH (1-24)
  • Sequence: SFS-(Nle)-EHFRWGKPVGKKRRPVKVYP
  • CAS Number: [97773-00-7]
  • Formula: C137H212N40O30
  • Characteristics: None
  • Reference: None
13.[Tyr15]-ACTH (7-15)
  • Name: [Tyr15]-ACTH (7-15)
  • Sequence: FRWGKPVGY
  • CAS Number: None
  • Formula: C55H76N14O11
  • Characteristics: None
  • Reference: None
14.Ac-ACTH (1-14), 10-1-12A
  • Name: Ac-ACTH (1-14), 10-1-12A
  • Sequence: Ac-SYSMEHFRWGKPVG
  • CAS Number: None
  • Formula: C79H111N21O21S
  • Characteristics: None
  • Reference: None
15.ACTH (1-4)
  • Name: ACTH (1-4)
  • Sequence: SYSM
  • CAS Number: [19405-50-6]
  • Formula: C20H30N4O8S
  • Characteristics: None
  • Reference: None
16.ACTH (1-14)
  • Name: ACTH (1-14)
  • Sequence: SYSMEHFRWGKPVG
  • CAS Number: [25696-21-3]
  • Formula: C77H169N21O20S
  • Characteristics: None
  • Reference: None
17.ACTH (1-39), guinea pig
  • Name: ACTH (1-39), guinea pig
  • Sequence: SYSMEHFRWGKPVGKKRRPVKVYANGAEEESAEAFPLEF
  • CAS Number: [111524-36-8]
  • Formula: C206H308N56O58S
  • Characteristics: None
  • Reference: None
18.ACTH (11-24)
  • Name: ACTH (11-24)
  • Sequence: KPVGKKRRPVKVYP
  • CAS Number: [4237-93-8]
  • Formula: C77H134N24O16
  • Characteristics: None
  • Reference: None
19.ACTH (12-39), rat
  • Name: ACTH (12-39), rat
  • Sequence: PVGKKRRPVKVYPNVAENESAEAFPLEF
  • CAS Number: None
  • Formula: C145H227N39O41
  • Characteristics: None
  • Reference: None
20.ACTH (22-39)
  • Name: ACTH (22-39)
  • Sequence: VYPNGAEDESAEAFPLEF
  • CAS Number: [37548-29-1]
  • Formula: C90H125N19O32
  • Characteristics: None
  • Reference: None
21.ACTH (3-24), human, bovine, mouse, ovine, porcine, rabbit, rat
  • Name: ACTH (3-24), human, bovine, mouse, ovine, porcine, rabbit, rat
  • Sequence: SMEHFRWGKPVGKKRRPVKVYP
  • CAS Number: [1036763-00-4]
  • Formula: C124H196N38O27S
  • Characteristics: None
  • Reference: None
22.ACTH (34-39)
  • Name: ACTH (34-39)
  • Sequence: AFPLEF
  • CAS Number: [69454-10-0]
  • Formula: C37H50N6O9
  • Characteristics: None
  • Reference: None
23.ACTH (4-9)
  • Name: ACTH (4-9)
  • Sequence: MEHFRW
  • CAS Number: None
  • Formula: C42H56N12O9S
  • Characteristics: None
  • Reference: None
24.Tyr-ACTH (4-10)
  • Name: Tyr-ACTH (4-10)
  • Sequence: YMEHFRWG
  • CAS Number: [131374-17-9]
  • Formula: C53H68N14O12S
  • Characteristics: None
  • Reference: None
25.ACTH (5-10)
  • Name: ACTH (5-10)
  • Sequence: EHFRWG
  • CAS Number: [4086-29-7]
  • Formula: C39H50N12O9
  • Characteristics: None
  • Reference: None
26.ACTH (7-38), human
  • Name: ACTH (7-38), human
  • Sequence: FRWGKPVGKKRRPVKVYPNGAEDESAEAFPLE
  • CAS Number: [68563-24-6]
  • Formula: C167H257N47O46
  • Characteristics: None
  • Reference: None
27.Tyr-ACTH (4-9)
  • Name: Tyr-ACTH (4-9)
  • Sequence: YMEHFRW
  • CAS Number: [129813-57-6]
  • Formula: C51H65N13O11S
  • Characteristics: None
  • Reference: None
28.Biotin-ACTH (18-39), human (Adrenocorticotropic Hormone)
  • Name: Biotin-ACTH (18-39), human (Adrenocorticotropic Hormone)
  • Sequence: Biotin-RPVKVYPNGAEDESAEAFPLEF
  • CAS Number: None
  • Formula: C122H179N29O38
  • Characteristics: None
  • Reference: None
29.Biotin-ACTH (1-39), human
  • Name: Biotin-ACTH (1-39), human
  • Sequence: Biotin-SYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEF
  • CAS Number: None
  • Formula: C217H322N58O60S
  • Characteristics: None
  • Reference: None
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