Sarafotoxin

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Sarafotoxins (SRTXs) are a kind of 21-residue cardiotoxic peptides from the snake venom. They can induce coronary vasoconstriction, bind to atrial an brain membranes with high-affinity. In order to activate the hydrolysis of phosphoinositides.

SRTXs induce toxicity because of the vasoconstriction. S6a and S6c can produce both vasodilation and vasoconstriction in the systemic vascular bed, in order to increase lobar vascular resistance.

Notice: All peptides are only for research purposes, Not for clinical use.

Sarafotoxin

1.(Nle6)-Sarafotoxin C
  • Name: (Nle6)-Sarafotoxin C
  • Sequence: CTCND-(Nle)-TDEECLNFCHQDVIW
  • CAS Number: [352283-69-3]
  • Formula: None
  • Characteristics: None
  • Reference: None
2.Sarafotoxin C
  • Name: Sarafotoxin C
  • Sequence: CTCNDMTDEECLNFCHQDVIW
  • CAS Number: [121695-87-2]
  • Formula: None
  • Characteristics: None
  • Reference: None
3.Sarafotoxin B
  • Name: Sarafotoxin B
  • Sequence: CSCKDMTDKECLYFCHQDVIW
  • CAS Number: [120972-53-4]
  • Formula: None
  • Characteristics: None
  • Reference: None
4.Sarafotoxin A
  • Name: Sarafotoxin A
  • Sequence: CSCKDMTDKECLNFCHQDVIW
  • CAS Number: [126738-34-9]
  • Formula: None
  • Characteristics: None
  • Reference: None
5.[Lys4]-Sarafotoxin S6c
  • Name: [Lys4]-Sarafotoxin S6c
  • Sequence: CTCKDMTDEECLNFCHQDVIW
  • CAS Number: [116495-45-5]
  • Formula: C105H153N27O36S5
  • Characteristics: (Cys1-Cys15, Cys3-Cys11 bridge)
  • Reference: None
6.Sarafotoxin S6b
  • Name: Sarafotoxin S6b
  • Sequence: CSCKDMTDKECLYFCHQDVIW
  • CAS Number: [116303-65-2]
  • Formula: C110H159N27O34S5
  • Characteristics: (Cys1-Cys15, Cys3-Cys11 bridge)
  • Reference: None
7.Sarafotoxin S6d
  • Name: Sarafotoxin S6d
  • Sequence: CTCKDMTDKECLYFCHQDIIW
  • CAS Number: None
  • Formula: C112H163N27O34S5
  • Characteristics: (Cys1-Cys15, Cys3-Cys11 bridge)
  • Reference: None
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